New Cancer Research for Dogs

[glencorgi]

While neither corgi breed is listed in the research, success here could lead to breakthroughs in the future.

Debbie


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Research Area: Canine Cancer
Breeds: Akita, American Cocker Spaniel, Boxer, Bullmastiff, Chinese
Shar-Pei, Chow Chow, English Cocker Spaniel, English Springer Spaniel,
Flat-Coated Retriever, German Shepherd, Giant Schnauzer, Golden
Retriever,
Greyhound, Labrador Retriever, Leonberger, Mastiff, Miniature Poodle,
Miniature Schnauzer, Pointer, Pug, Rottweiler, Scottish Terrier,
Standard
Poodle, Standard Schnauzer, Toy Poodle

After completing the dog genome sequencing project, the Broad
Institute of
Harvard and MIT and collaborators are now working on identifying disease
genes predisposing to cancer. Identification of such genes could lead to
carrier testing, a better understanding of the disease and long term
better
treatments for the disease in both dogs and humans. More information
can be
found at: www.broad.mit.edu/mammals/dog.

For each of the below diseases researchers need blood samples from
affected
dogs as well as blood samples from healthy older (>6 yo) dogs.

3. Mammary tumors

PI: Kerstin Lindblad-Toh Broad and Elizabeth McNiel, U. Minnesota
Focus: English Springer Spaniel
Additional breeds included: German Shepherds, Cocker Spaniels and Boxers
Please contact: Dog-info@broad.mit.edu <mailtoog-info%40broad.mit.edu>

4. Melanoma

PI: Kerstin Lindblad-Toh Broad and Phil Bergman, Animal Medical
Center, NY
Breeds included: ALL including Scottish Terriers, Cocker Spaniels, Black
Labrador Retrievers, Rottweilers, Chow Chows, and Pugs
Please contact: Dog-info@broad.mit.edu <mailtoog-info%40broad.mit.edu>

5. Lymphoma

PI: Kerstin Lindblad-Toh, Broad
Focus: Golden Retrievers, Boxers
Additional breeds included: Cocker Spaniel, Rottweiler, Akita, Flat-
Coated
Retriever
Please contact: Dog-info@broad.mit.edu <mailtoog-info%40broad.mit.edu>

6. Mast cell tumors

Collaborators: Kerstin Lindblad-Toh, Broad and Cheryl London, UC Davis
Focus: Pugs and Chinese Shar-Pei
Additional breeds included: Pit Bull Terrier, Labrador Retriever, Golden
Retriever, German Shepherd, Cocker Spaniel, Boxer
Please contact: Dog-info@broad.mit.edu <mailtoog-info%40broad.mit.edu>

Researchers at the AMC Cancer Research Center and University of Colorado
Health Science Center are looking for samples for the following
projects:

7. Lymphoma

Researchers need samples from any dog that has an AKC registration
number.
Eligible dogs will undergo standard of care treatment and provide blood
samples as well. Availability of 2 or more unaffected relatives that
are >6
years old is desirable. They also would encourage people who have
dogs that
are related to study subjects that are affected to participate.
Owners of
all dogs will be asked to fill out a follow-up questionnaire.

8. Hemangiosarcoma

Researchers need blood samples from affected dogs for a study to map
susceptibility genes. In some cases, samples may be applied to the
development of a diagnostic test for hemangiosarcoma. Eligible dogs must
have an AKC registration number. Owners of all dogs will be asked to
fill
out a follow-up questionnaire.

Visit www.modianolab.org for additional information on these programs.

[Chip's Mom]

That would be so wonderful if that happened.

[Jespah]

I hope that this will help anyone in the future and that dogs and their "parents" won't have to go through what we are.

[Chip's Mom]

Our thoughts and prayers go with you - It is so hard. How are things going? How are you doing?

[corgimom]

Yes, I would love to know how Riley is feeling today and is she able to eat
more regular food - I thought you said that by this Monday, you would know?

Linda

[Jespah]

Hi Ladies,

Riley has done very well. She had no reaction to the chemo, other than being a little tired. She spent both Saturday and Sunday AM down in the lake - an hour and half solid yesterday until I forced her out. I'm making sure she's getting rest to compensate. She's on steroids that are making her very hungry and thirsty, so one of my wonderful neighbours is taking the two of them out for a tinkle in the middle of the day for me while I'm at work and giving Riley an extra meal. She had some of the cookies that fell out of their treat ball and wasn't sick, so I'm hopeful she'll be able to tolerate more solid food. She's eating more at each meal and hasn't been sick since last Tuesday. She gets different drugs at this week's treatment, so we'll see how she does with them. I am hopeful, but also rooted in reality. I'll take every good day and am prepared for the worst. She's happy and still flipping her 10 pound heavier brother and pinning him, so all is currently good.

Thanks for asking about her,

Deb

[glencorgi]

Oh Deb,

Wonderful news! The spirit these guys have is amazing and inspirational! Hugs to all of you!

Debbie

[corgimom]

Such good news to near that she still wants to "wrestle".

Linda